Cholinesterase inhibitors

Domain : Support

Simplified definition

A class of drugs that prevent the destruction of a molecule called “acetylcholine”, thus increasing its concentration in the body and the communication between neurons.

Source: Houria Aiouaz, for Alzheimer Foundation

Referenced definition

“[…] Chemicals whose primary toxic effect is to block the normal breakdown of the neurotransmitter, acetylcholine.”

Source: ATSDR. Part 2: What are cholinesterase inhibitors. [Internet]. [cited on Sept 7, 2022]. 

Context

Cholinesterase inhibitors are the most common medications used for the symptomatic treatment of Alzheimer disease. Data from published clinical trials have shown benefits for cognitive, behavioral, and functional outcomes.”

Source: Lee PE, Hsiung GYR, Seitz D, Gill SS, Rochon PA. Cholinesterase inhibitors. BC Medical Journal. 2011;53(8):404-408.

 

 

Note

  • Acetylcholine is involved in memory and moves information from a neuron to another.
  • An elevated concentration of acetylcholine in the body can be harmful.

Synonym(s)

Acetylcholinesterase inhibitors / Anticholinesterase drugs

Cholinesterase inhibitors : RELATED DEFINITIONS

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